| Guest Name | Information | Last Appearance |
|---|---|---|
| Herman Cain | Former Presidential Candidate | February 17, 2012 |
| John Cameron | President, The Safe Cig | April 24, 2012 |
| Bill Campbell | Chairman of the Board, Intuit | May 12, 2012 |
| Jamie Campolongo | CEOPittsburgh Transportation Group | |
| Linda Capcara | Principal/Founder, Global Connect Communications LLC | June 19, 2012 |
| Babs Carryer | Adjunct Faculty, Carnegie Mellon University | June 1, 2012 |
| Dr. Ben Carson | Director of Pediatric Neurosurgery, Johns Hopkins University | |
| Leonard Casson | Associate Professor, Civil EngineeringUniversity of Pittsburgh - Swanson School of Engineering | May 3, 2012 |
| Jim Cawley | Lieutenant Governor | August 22, 2011 |
| John Challenger | CEO, Challenger, Gray, Christmas | September 12, 2011 |
| Jack Chambless | Professor of Economics, Valencia College | February 27, 2012 |
| Ram Charan | Business Consultant | September 6, 2010 |
| Ray Charley | President, Shop-N-Save | January 10, 2012 |
| Don Charlton | Founder & CEOThe Resumator -- Hire With Confidence™ | |
| Jeff Clavier | Managing Partner, SoftTech VC | May 5, 2012 |
| Will Clower | Doctor | April 16, 2012 |
| Rob Cochran | President & CEO#1 Cochran | July 26, 2010 |
| Mike Coffee | Chief Business Officer, Medicinova | June 6, 2012 |
| Matt Coffey | Chief Operating Officer, Oncolytics Biotechnology | May 2, 2012 |
| Jim Collins | Author, Good to Great | November 3, 2011 |
| Eric Cook | "Eric the Car Guy" | March 5, 2012 |
| Trevor Corson | Author / Public Speaker | December 8, 2010 |
| Dan Courser | PresidentPredictive Synergistic Systems | |
| Stephen M.R. Covey | Co-founder & CEO, CoveyLink World Wide | November 22, 2010 |
| Stephen Covey | Author, Seven Habits of Highly Effective People | |
| Jerry Cozewith | President, Entrepreneuring Youth | May 24, 2012 |
| Austin Craig | Spokesman, Orabrush | March 31, 2012 |
| Robert Crandall | President, American Airlines | September 15, 2011 |
| Mike Critelli | CEO, Dossia | January 2, 2012 |
| Kevin Crone | CEO, Dale Carnegie Business Group | March 14, 2012 |
| Samuel Culbert | Professor, UCLA Anderson School of Management | April 14, 2010 |