| Guest Name | Information | Last Appearance |
|---|---|---|
| Craig Newmark | Founder, Craigslist | July 12, 2010 |
| Jim Newton | Chairman/Founder, TechShop | |
| Mike Novak | Senior Account Executive, Rodata | November 1, 2011 |
| Jean Novak | AttorneyStrassburger McKenna Gutnick & Gefsky | March 31, 2012 |
| Gary Novak | Chairman, Lunova | April 9, 2012 |
| Rob O'Donnell | Managing Director, Consulting ServicesSolutions 21 | May 1, 2012 |
| Jason O'Neill | Founder, Pencil Bugs | August 6, 2010 |
| Joe Oestreicher | Director of U.S. RecruitingBayer Corporation | April 30, 2012 |
| Brian Oram | Geologist, Licensed Well Driller, B.F. Environmental Services | May 4, 2012 |
| Cal Orey | Freelance writer | March 3, 2012 |
| Dan Ostlund | Technician, Fog Creek Software | January 9, 2012 |
| Jack Ouellette | CEO, American Textile | October 18, 2011 |
| Rich Overmoyer | CEO, Fourth Economy | October 18, 2010 |
| Joe Pappalardo | Senior News Editor, Popular Mechanics | June 8, 2012 |
| Chris Parry | CEO, encompass Technology Solutions | March 18, 2012 |
| Seema Patel | Founder and CEO, Interbots | May 21, 2012 |
| Aaron Patzer | Founder, Mint.com | July 29, 2010 |
| Jayne Pearl | Author, Kids, Wealth, and Consequences: Ensuring a Respons | July 14, 2011 |
| Diane Pearson | Advisor and ShareholderLegend Financial Advisors, Inc.® | June 15, 2012 |
| Corey Perlman | Social Media Expert & Best-Selling Author, eBoot Camp | July 28, 2011 |
| Paul Petrovich | Assistant Director OED Business DevelopmentUniversity of Pittsburgh - Swanson School of Engineering | April 9, 2012 |
| Rob Pfaffman | Founder, Pfaffmann & Associates | September 17, 2010 |
| Laura Piel | President, Renaissance Partners Group | April 9, 2012 |
| Lily Pietryka | Founder Global Link LLC, Global Link LLC | March 1, 2011 |
| Matt Pitzarella | Director of Corporate CommunicationsRange Resources | June 15, 2012 |
| Jeff Platt | Co-Founder, Skyzone Sports | April 13, 2011 |
| Doug Porter | CEO, Ronald McDonald House Charities | May 30, 2012 |
| Chris Posti | HR Consultant, Posti & Associates | June 11, 2012 |
| William Poundstone | Author | March 21, 2012 |
| Jessica Prentice | Author, Full Moon Feast:Food And The Hunger For Connection | October 29, 2011 |
| Jessica Prentice | Author, Full Moon Feast: Food and The Hunger for Connection | June 9, 2012 |
| Bryan Putt | President, AIReS | April 9, 2012 |
| Richard Rahn | Senior Fellow, Cato Institute | April 26, 2012 |
| D. Raja | Candidate, Pennsylvania State Senate | May 19, 2012 |
| J.J. Ramberg | Host, MSNBC's | March 1, 2012 |
| Ripa Rashid | Senior Vice President, Center for Work-Life Policy | April 9, 2012 |
| Horst Rechelbacher | Founder, Aveda Health Care Products | March 30, 2011 |
| Mark Redfern | Associate Dean of Research, Swanson SchoolUniversity of Pittsburgh - Swanson School of Engineering | April 9, 2012 |
| Greg Reed | Associate Director for the Center of Energy, University of Pittsburgh | |
| Tony Ricciardi | President/Co-Founder, Listen Up Espanol | April 9, 2012 |
| Chet Richards | Author, Certain to Win | April 9, 2012 |
| Matthew Richardson | Charles Simon Professor of Applied Financial Econ., New York University | January 23, 2012 |
| Raymond Richman | Economics Professor, University of Pittsburgh | February 18, 2012 |
| Howard Richman | Principal, Ideal Taxes Association | January 7, 2012 |
| Dan Roam | Author, The Back of the Napkin | April 9, 2012 |
| Alish Roarty | Training Program Leader, Clinical Labratories | June 12, 2012 |
| Mark Roberti | Founder & Editor, RFID Journal | February 9, 2011 |
| James Roddey | President of the Board of Directors, RiverQuest | April 9, 2012 |
| Gay Rodgers | Owner/Director, Hameau Farms | January 18, 2012 |
| John Rodgers | CEO, Dale Carnegie Systems/JR Rodgers and Associates | April 16, 2012 |