| Guest Name | Information | Last Appearance |
|---|---|---|
| Omar Soliman | Co-founder/CEO, College Hunks Hauling Junk | September 27, 2010 |
| Daniel Sperling | Founding Director, Institute of Transportation Studies | March 23, 2010 |
| Jack Stack | President & CEO, SRC Holdings Corporation | November 11, 2010 |
| Lou Stanasolovich | PresidentLegend Financial Advisors, Inc.® | April 18, 2012 |
| Bob Stearns | CEO, Powerful Potential | May 18, 2012 |
| Jasia Steinmetz | Author, Eat Local: Simplle teps to Enjoy Real, Healthy & Affordable Food | June 9, 2012 |
| David Stern | President & CEO, Paris Company | July 8, 2011 |
| John Stollenwerk | CEO, Allen Edmonds | October 14, 2010 |
| Rick Stouffer | Editor-in-Chief, Gas Business Briefing | May 25, 2012 |
| Louis Straney | Founder/CEO, Arbitration Insight llc | January 4, 2012 |
| Bill Strickland | President & CEO, Manchester Craftsmens Guild | March 10, 2011 |
| Mike Stubler | Managing Director/Co-Founder, Draper Triangle Ventures | December 3, 2011 |
| Geoff Styles | Managing Director, GSW Strategy Group, LLC | April 20, 2012 |
| Jay Sukits | Clinical Assistant Professor of Business Admin., University of Pittsburgh | June 1, 2012 |
| Bob Sullivan | Consumer Expert / Author / Journalist, MSNBC | |
| Rob Tannenbaum | Author, "I Want My MTV" | May 7, 2012 |
| Heather Terry | Founder/CEO, NibMor | September 8, 2011 |
| Mike Testa | President, Testa Consulting | May 1, 2012 |
| Paul Teutul Sr. | Founder, Orange County Choppers | |
| Robert (Bob) Thacker | Director, PA Gunsmith School | August 3, 2011 |
| Fred Thieman | President, Buhl Foundation | October 25, 2012 |
| Bethany Thomas | TeacherPropel Schools | June 16, 2011 |
| Alvin Toffler | Business Author / Futurist | September 6, 2010 |
| Chris Trimble | Author, Reverse Innovation | June 13, 2012 |
| Jack Trout | President / Author - "Positioning: The Battle For , Trout & Partners, Ltd. | |
| Dorothy Tuel | President, Sewickley Spa | September 16, 2011 |
| Christine Tumpson | Editor in ChiefWHIRL Magazine | October 1, 2011 |
| Jack Tumpson | PublisherWHIRL Magazine | October 1, 2011 |
| Frons Tunistra | Trombly International | December 8, 2010 |
| Divyank Turakhia | Co-Founder / President, Dircti | |
| Mike Turzai | State Representative, PA 28th Legislative District | March 30, 2012 |
| Paco Underhill | Author, Why We Buy: The Science of Shopping | March 23, 2012 |
| Raul Valdes-Perez | Executive Chairman, Vivisimo | April 21, 2012 |
| Julie Vandenbossche | Assistant Professor, Geotechnical and Pavements En, Swanson School of Engineering - University of Pitt | January 27, 2012 |
| Laura Vanderkam | Author | February 1, 2011 |
| John Vechey | Founder, Popcap Games | |
| Richard Vedder | Professor, Center for College Affordability and Productivity | April 16, 2012 |
| Lillian Vernon | Founder, The Lillian Vernon Corporation | |
| Chuck Verrett | President and Founder, Integra Marketing Group | June 5, 2012 |
| Radisav Vidic | Professor of Environmental EngineeringUniversity of Pittsburgh - Swanson School of Engineering | December 9, 2011 |
| Valerie Voss | CPAWilke & Associates, LLP | November 26, 2011 |
| Sunil Wadhwani | Co-Founder / CEO, IGate | |
| Lisa Wagner | Board President, Crisis Center North | April 19, 2012 |
| Ray Walker Jr. | Senior VP - COORange Resources | |
| Steve Wallach | CEO, Youngevity | April 4, 2012 |
| Craig Waller | Attorney, Ference & Associates | April 13, 2011 |
| John Walsh | Owner, Bethel Bakery | May 24, 2012 |
| Jeff Wangler | Vice President, AIReS | April 9, 2012 |
| Benjamin Wasson | Student, Chartiers Valley High School | April 5, 2012 |
| Rob Watson | Chairman, CEO and Chief Scientist, Ecotech International | June 14, 2012 |